Erectile dysfunction (ED) is the common type of sexual disorder in men in which a man is not able to obtain or maintain an erection of penis for long duration of time. This causes a dissatisfaction among partners and disrupts their sexual life. There are several causes of developing ED like stress, anxiety, obesity, diabetes etc. Treatment with medicines is widely prescribed. The medicines belonging to class of PDE-5 inhibitors are often the drugs of choice.
Mechanism of action of Sildenafil Citrate
Sildenafil Citrate prevents the degradation of cGMP by inhibiting PDE-5 enzyme which increases the levels of CGMP in the penile region. This leads to relaxation of smooth muscles inside penis and dilation of blood vessels supplying blood to the penis. The dilated blood vessels allow more amount of blood to enter the penis which results in a firm and strong penile erection required for successful vaginal penetration. This is gives both the partners complete sexual satisfaction and complete sexual pleasure.
Onset of action and Duration of effect
The action of this medicine is observed within 30 minutes to 120 minutes after taking the medicine orally. The onset of action differs from person to person. The effect of this medicine lasts for period of 4 hours.
How to take Sildenafil Citrate?
Follow all the instructions given on the prescription label. Take in amount and for the time as advised by your physician. The most widely prescribed dose of Sildenafil Citrate is 100mg daily. This medicine is to be taken 45 minutes to 60 minutes before making love. There are no food interactions reported, so, you can take Generic food with food or without food.
What are the instructions to be followed while taking Sildenafil Citrate?
If you missed the dose take it as soon as you remember. Skip the dose if it’s already the time to take the next scheduled dose. Do not take an extra dose to compensate for missed dose. Seek immediate medical attention if an overdose is suspected. Give you doctor your complete medical history before starting treatment with this medicine. Avoid driving and operating machinery while taking Sildenafil Citrate as it may induce drowsiness. The use of Sildenafil Citrate in pregnant women, nursing mothers and men below 18 years of age is not recommended. Avoid use of alcohol, tobacco, grapefruit products, nitrate drugs, alpha blockers, fatty food and other PDE-5 inhibitors with Sildenafil Citrate as they interact to produce undesirable effect.
What are the likely side effects?
Some of the likely side effects of Sildenafil Citrate which subside after discontinuing the medicine are headache, vision changes, back ache and muscle pain, facial flushing, nasal congestion, nausea and vomiting, dizziness, diarrhea, skin rash.
2 Weeks Ago, Tuesday, May 15, 2018, 07:23:12